Description
DMAE can be found in various memory enhancing formulations these days, It is found in sardines and anchovies[4]. The compound is a biological precursor to Acetylcholine[4], a vital neurotransmitter which affects memory and learning[1]. Unlike other precursors however, it also decreases theta and alpha1 activity in the brain[2]. This effect is associated with the increased vigilance and mood characterized by DMAE[2]
Benefits
- Working Memory[3]
- Choline Precursor[4]
- Attention[2]
- Mood[2]
- Lucid Dreaming
- "inhibits the formation of ageing pigment (lipofuscin) and flushes it from the body"[5]
Research
"Subjects taking [a vitamin-mineral drug combination containing dimethylaminoethanol (DMAE)] for 3 months developed significant less theta and alpha1 power in sensomotoric areas of the cortex. Since decreases in theta and alpha1 electrical power have been associated with increased vigilance and attention, subjects taking the drug combination obviously were more active and felt better. Both scores revealed a better mood for the active drug group thus corroborating the results from EEG analysis. Therefore the vitamin-mineral drug combination containing DMAE can be interpreted to induce a psychophysiological state of better feeling of wellbeing on both levels of analysis mood and electrical pattern of brain activity in subjects suffering from borderline emotional disturbance."[2]
"One of the three compounds tested, DMAE II (dimethylaminoethanol cyclohexyl carboxylate fumurate), produced significant improvements in working memory performance [in rats]"[3]Warning
The jury is still uncertain as to whether or not DMAE will extend or decrease life in humans. In mice, DMAE was found to increase lifespan. In Japanese Quails, however, it was found to decrease. Although it would be safer to assume the fate of the mouse, there has yet to be any conclusive evidence showing life span increase in humans. Given the beneficial effects of this compound, I myself lean towards its anti aging effects.
References
[1] (Wikipedia Entry: Acetylcholine)
[2] Stimulant Effect of 2-Dimethylaminoethanol—Possible Precursor of Brain Acetylcholine
[3] Effects of nicotinic dimethylaminoethyl esters on working memory performance of rats in the radial-arm maze.
[4] (Wikipedia Entry: DMAE)
[5] Synthetic drugs with anti-ageing effects
how do you think this would go in combination with bacopa? and if i were to combine the two, what else would you recommend? maybe ... ah! what's that andean root you mentioned the other day? the one with the endocrine precursors...
ReplyDeleteNot sure as far as the endocrine precursors. I have seen the usage of DMAE with Bacopa. I think it's a rather nice combination, the DMAE enhances the presence of EEGs associated with vigilance sometimes forgoing creativity for precision from personal experience. The Bacopa might remedy this as well as taking away the overstimulation that is commonly mentioned for DMAE.
ReplyDeleteI wouldn't view it similar to a stimulant because its mechanism of action isn't similar to any of the stimulants (ADHD type). Its effects are certainly different as well.