Description
L-Theanine is the active amino acid found in tea (Camellia sinensis). It is the compound responsible for the relaxing effect found within tea. Research has shown that the effects of L-Theanine seem to reduce the stimulatory effects of caffeine as measured by the EEG response[2]. It promotes the release of Serotonin and Dopamine in the brain and promotes the alpha brainwave associated with relaxation[1]. In addition to these benefits it appears to have anti-tumor effects.Research
"Theanine crosses the blood-brain barrier via the large neutral amino acid (leucine-preferring) transport system. Theanine, when reaching the brain, has been shown in rats to increase both serotonin and dopamine production."[1]
"L-theanine has been studied extensively for its effects on tumor cells and the sensitivity of those cells to chemotherapeutic agents. It appears theanine competitively inhibits glutamate transport into tumor cells, which causes decreased intracellular glutathione (GSH) levels. Theanine also inhibits the efflux of chemotherapeutic agents, such as doxorubicin, idarubicin, cisplatin, and irinotecan, causing them to accumulate in tumor cells. Theanine also protects normal cells from damage by these drugs via antioxidant activity, specifically by maintaining cellular GSH levels.7-10"[1]
"Studies show L-theanine induces alpha-brain wave activity, which correlates with a perceived state of relaxation. A small Japanese study of university students showed oral L-theanine administration of 200 mg led to increased alpha-brain waves and a subjective sense of relaxation. Theanine administration caused a dose-dependent relaxed, yet alert, state of
mind without sedation, beginning approximately 40 minutes after oral dosing. 6"[1]
References
[1] L-Theanine Monograph
[2] L-Theanine and EEG Response
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